Patrick Pettiford gained all of his game high 142 yards in the first half as Orange took a 56-7 victory away from its road trip to Oxford Webb.
Friday’s win sets up next week's Big-8 Conference showdown in Hillsborough between (9-0 overall, 5-0 conference) and Cardinal Gibbons (7-2, 4-1).
Orange needed little time Friday to show why it's North Carolina's No. 7-ranked 3A team in the Associated Press poll. Webb had no answer for the explosive Panthers, who scored on five of their first six possessions.
Orange quarterback Garrett Cloer threw three touchdown passes in the first half — 15 and 16 yards to Ky Muller and a 54-yard strike for a catch-and-run for Tay Jones — helping the Panthers take a 42-0 lead after two quarters.
Jones later added a 58-yard touchdown run.
Patrick Pettiford opened the night’s scoring with a 55-yard dash on Orange's first possession and Michael Bolden scored on a 4-yard plunge to end the second drive.
"We starte quick. Pat Pettiford made that good run right at the start of the game and I think everybody got inspired," Orange head coach Pat Moser said. "Our defense has always been there, but I think our offense showed back up tonight."
Orange took a 28-0 lead as the first quarter expired on a 92-yard punt return for a touchdown by J.D. Brooks. He capped Orange's scoring with an 85-yard interception return for his second score.
Webb (2-7, 0-5) avoided the shutout with a 5-yard touchdown run by Tevin Evans with 2:54 to play in the game.
With Brooks scoring twice, Orange's offense rolled up "only" 360 yards. The Panthers, forcing four turnovers, held Webb to just 40 yards in the first half, 120 yards of total offense for the night.
In other games Friday, East Chapel Hill kept its playoff hopes alive with a 42-35 win at Roxboro Person, Chapel Hill fell 47-36 at Cardinal Gibbons, Northwood blew past Northern Vance 51-17, and Cedar Ridge couldn't stop Southern Durham in a 68-10 Spartan win.
At Raleigh, Chapel Hill led by 10 with 10:51 remaining in its Big-8 game at Cardinal Gibbons, but Shawn Stankavage threw two touchdown passes and ran in a score himself to rally the Crusaders to their fifth straight win over the Tigers.
For the second straight week, the Tigers (3-6, 2-3 Big-8) nearly toppled a team with its sights set on the league title. Last week undefeated Orange scored at the end of the game to edge the Tigers 6-0.
"Chapel Hill came in here and gave us all we could handle," said Gibbons coach Steven Wright, whose team lost to league foe Southern Durham. "And now we know we've got to win next week to have a chance at the conference title. I haven't heard the score, but I'm pretty sure we're going to play an undefeated Orange team."
At Roxboro, East Chapel Hill (2-7, 1-2 PAC) trailed 28-26 with five minutes left before Colby Owens capped two Wildcat drives with touchdowns and 2-point conversions, the last with 1:50 showing on the clock. Person tacked on a late score, but the Wildcats grabbed the ensuing onside kick to secure their first conference win – their third straight against the Rockets in three years.
Owens ended up with 160 yards and five touchdowns total on 20 rushes.
At Henderson, Kadarus Rone scored on a 3-yard run 3:58 into Northwood’s game at Northern Vance, sparking the Chargers (7-2, 3-2 Big-8) to a 21-point first quarter. He finished with 123 yards on just 9 carries, while teammate Montel Goods rushed 18 times for 106 yards and two touchdowns.